Genomics:GTL

Six histidine

Purification by immobilized metal affinity chromatography (IMAC)

Epitope (e.g., myc, V5, FLAG, soft-epitope)

Detection with antibodies, purification, immunoprecipitation

StrepTag

Purification with streptavidin

S tag

Purification, detection

AviTag, Pinpoint

In vitro or in vivo biotinylation

Tandem affinity (TAP)

Purification

Tetracysteine

In vivo labeling, purification

Lanthanide-binding peptide

Labeling

Coiled-coil

Heterodimerization with partner peptide (e.g., E coil with K coil)

Metal, semiconductor, or plastic binding peptides

Immobilization on surfaces, nucleation or growth of nanocrystals, detection of semiconductor materials

Calmodulin-binding peptide

Purification (Ca²⁺ dependent)

Elastin-like peptides

Purification (temperature-dependent aggregation)

Fusion partners (glutathione-S-transferase, maltose binding protein, cellulose-binding domain, thioredoxin, NusA, mistin)

Promotion of folding, solubility, expression, or purification of fused protein

Chitin-binding domain

Promotion of folding, solubility, expression, purification, immobilization

Green fluorescent protein or alkaline phosphatase

Monitoring of expression, purification, or binding of fusion partner

Cutinase, O⁶-alkylguanine alkyltransferase (AGT), or halo tag

Covalent modification for immobilization, purification, or detection

Intein

Chemical ligation in vitro or in vivo